PROJECTS

International and national projects:

• HUMAN BIOLOGICAL RESOURCES CENTER (HBRC) (2019-2023)

• Grand Challenge Project (Mutographs), Cancer Research UK (CRUK)

• SPECTA: Screening Cancer Patients for Efficient Clinical Trial Access, EORTC (2019-2024)

https://spectaplatform.org/ 

• The Cancer Tissue Genome Atlass (TCGA) (2013-2023)

https://www.cancer.gov/about-nci/organization/ccg/research/structural-genomics/tcga

• “Radiogenomic patterns of BRCA1/2 breast cancer” joint Japanese project, Ministry of Health of the Republic of Lithuania (2021-2024)

• European Network of Excellence for Big Data in Prostate Cancer “PIONEER”, H2020 and EFPIA, molecular data research group. https://prostate-pioneer.eu/

• COST Action initiative: “Converting molecular profiles of myeloid cells into biomarkers for inflammation and cancer (Mye-InfoBank)” CA20117 (2021-present) https://www.mye-infobank.eu/home.html

NCI scientific research topics in which Biobank employees participate:

• Laboratory of Cancer Epidemiology “Use of Antihypertensive Drugs and Survival in Cancer Patients” (2021-2024).

• Laboratory of Molecular Oncology “Search for Predictive Markers of Triple-negative Breast Cancer” (2019-2023).

• Biobank initiated project “Fertility Preservation Program for Oncology Patients”.

The Biobank leads the project (collection, processing, preservation and storage of reproductive tissues and germ cells). The Oncourology, Oncogynecology and Breast Surgery and Oncology Departments participate in the patient selection and tissue collection processes (Protocol No. III-2014-1, Bioethics Committee 2014-07-08 permit No. 158200-14-743-260, 2014-2024.

Completed projects initiated by Biobank or carried out in cooperation with NCI departments and units:

• Breast Surgery and Oncology Department

“Significance of DNA Repair System Gene Expression in Predicting Postoperative Treatment of Patients with Stages IB-IIIA Non-small Cell Lung Cancer” (2011-2015).

“Exploration of Factors Influencing the Effectiveness of Treatment in Women with Lung Cancer” (2013-2017).

• General and Abdominal Surgery and Oncology Department

“Polycyclic Aromatic Hydrocarbons, DNA Adducts and Pancreatic Cancer” (Bioethics Committee permit No. 158200-15-776-293, 2015/03-2016/04).

• Laboratory of Immunology

“Significance of Cytostatics Fixation in Tissues for Response After Neoadjuvant Treatment” (2019-).

“Personalization of Therapeutic Mesenchymal Stem and Dendritic Cell Vaccines in Oncology Patients” (2010-2015).

• Biobank initiated topics

“Expression Studies of E3 Ubiquitin Ligases FBW7 and MDM2 and Their Substrates in Samples of Dysplastic Moles and Melanoma Patients” (2016-2020).

Completed international projects:

• International COST program: “Developmental origins of chronic lung disease” BM1201 (2013-2015).
• EU joint program: “Development of Skin and Lung Cancer Spectroscopic Image Archive and Remote Information Transmission Network” No. LLB-2-242 (2013/10 – 2015/11).
• EU Twinning program: “Improvement of quality of the National Cancer Screening Programmes implementation” (CRO SCREENING); Twinning Number: HR 14 IB SO 01.
• HORIZON 2020 project “Bridging Biobanking and Biomedical Research across Europe and Africa(B3Africa))” EC contract No 654404 (test user).